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NOBEL PRIZE 2026

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NIHNATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASESR01

BRinging the Diabetes Prevention Program to GEriatric Populations (BRIDGE)

Active
Institution
NEW YORK UNIVERSITY SCHOOL OF MEDICINE, NY
Principal investigator
Jeannette Michele Beasley
Funding
$688K
Duration
2021–2026
Open portfolio

Moonbase score

Still being scored

Abstract

PROJECT ABSTRACT Over 24 million Americans are ≥65 years and have prediabetes. Prediabetes can be addressed using a public health approach: among the 20% of participants in the Diabetes Prevention Program (DPP) who were ages 60 and over, the diet and physical activity intervention conferred a 71% risk reduction of diabetes after an average follow-up of 3 years. The population of older adults is projected to more than double from 52.5 million in 2019 to ~100 million by 2060, and if projections hold, about half (48.3%) will have prediabetes. The proposed study will compare a DPP program Tailored for Older Adults and delivered via Telehealth (DPP-TOAT arm) to an in person DPP tailored for older adults (DPP arm) using a randomized, controlled trial design (n=230). Our preliminary data suggests DPP-TOAT is a feasible and acceptable way to deliver the DPP to older adults, and this will be the first study to compare the effectiveness and implementation of two strategies (telehealth versus in-person) to deliver a tailored DPP for the unique needs of the growing population of older adults. Eligible patients will be recruited through electronic health records (Epic and MyChart) and randomized to the 12-month DPP-TOAT or the in-person DPP program. The primary effectiveness outcome will be 6-month weight loss and implementation outcome will be attendance. We will use a pragmatic approach in order to inform future studies conducted in community-based and rural settings. Findings will inform best practices in the delivery of an evidence-based intervention that could reach the 24+ million adults aged 65 and over with prediabetes.

Research team

  • Jeannette Michele BeasleyPI
  • Joshua ChodoshPI

LOADING MOONBASE SCORE

R01NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASESLifestyle Change and Behavioral Health Study Section[LCBH]oldertelehealtholder adultsprediabetesdiabetes preventionstudy comparedppprevention program

Questions for NEW YORK UNIVERSITY SCHOOL OF MEDICINE

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Same researchers, same institution, same topic, scored first.