ANNOUNCEMENT

NOBEL PRIZE 2026

This year's laureates, their fields, and the discoveries that earned them the prize.Live nowSee the winners
Moonbase
← Back to Awards
NIHNATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERINGR01

Connectome style neuroimaging in non human primates via novel integrated RF platforms

Active
Institution
UNIVERSITY OF MINNESOTA, MN
Principal investigator
Jan Zimmermann
Funding
$508K
Duration
2022–2026
Open portfolio

Moonbase score

Still being scored

Abstract

PROJECT SUMMARY Ultra high field neuroimaging in humans enables unprecedented resolutions that enable, for the first time, the non invasive investigation of directional information processing in vivo. These advances result from the ability of high resolutions to uncover layer specific (feedforward, feedback) activation patterns. These tools however are not validated in translational models that mimic human brain function. The reason for that is primarily due to our current inability to obtain functional magnetic resonance imaging (fMRI) signals at resolutions high enough to resolve layer specific responses in the non human primate. This project aims at developing novel and innovative radiofrequency hardware and using it at the ultra high field strength of 10.5 Tesla to directly test how well whole brain directional connectivity estimates from fMRI correspond with ground truth tract tracing experiments. This development and validation can directly aid us in translating findings from the animal model into future studies of the mesoscopic circuit effects of human mental illness.

LOADING MOONBASE SCORE

R01NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERINGEmerging Imaging Technologies in Neuroscience Study Section[EITN]ultralayerneuroimagingdirectionalteslaresolutionsnonfmri

Questions for UNIVERSITY OF MINNESOTA

Answered by the team behind this research.

No questions yet. Sign in to ask the first one

Related grants

Same researchers, same institution, same topic, scored first.