Bioenergetics Core

Project Summary – Bioenergetics Core Bioenergetic measurements using contemporary live-cell metabolic assay platforms provides insights into various parameters of energy metabolism. Complemented by established flow cytometry assay platforms to measure different mitochondrial and cellular functional parameters, the Bioenergetics (Bio-E) core will form a key component of Arkansas Integrative Metabolic Research Center (AIMRC). The Bio-E core will be a new core created to meet the metabolic research needs of the proposed COBRE center. The Bio-E core will coordinate closely with the AIMRC Imaging and Spectroscopy and Data Science Cores to generate a cross-disciplinary framework and allow project leaders to shed new light on cell and tissue metabolism, thus enabling novel discoveries, as well as clinical translation of such discoveries. Close collaborative interactions between the Bio- E Core and COBRE project leaders as well as the Imaging and Spectroscopy and Data Science Cores will lead to new innovations in research methods that will benefit future COBRE investigators as well as the broader campus research community. Hands-on training in live-cell metabolic assays and flow cytometry technologies will be provided to Center members, the campus and biomedical researchers in Arkansas.