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NOBEL PRIZE 2026

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NIHNATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES

Clinical Studies Core

Active
Institution
LA JOLLA INSTITUTE FOR IMMUNOLOGY, CA
Principal investigator
Alessandro Sette
Funding
$41K
Duration
2019–2029
Open portfolio

Moonbase score

Still being scored

Abstract

CORE B, CLINICAL CORE SUMMARY The success of the entire program is contingent upon successful accrual of human samples. The purpose of Core B (Clinical Core) is to provide a centralized resource for the accrual of human lymph node (LN), head and neck, nasopharyngeal swab (NP), peripheral blood mononuclear cells (PBMC), and sera and/or plasma samples. This Core will also ensure the quality and uniformity of handling samples received. In addition to recruitment goals, the goal of this Core is to design, establish, and maintain IRB approval while overseeing the quality control of coded clinical information and donor samples. These functions are crucial to provide a strong foundation for the studies described in the three proposed projects. The Core will be based at LJI at the John and Susan Major Center for Clinical Investigation, the CCHI’s home institution. The Clinical Core will work closely with subcontracts (Liverpool, U.K. and UCSD) to enable the acquisition of additional samples for Projects 1 and 3.

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NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASESU19ZAI1-AM-Icontingentsamplesuniformityaccrualestablish maintainpbmcserahome institution

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