Next Generation Sequencing Core (NGS)

PROJECT SUMMARY – NEXT GENERATION SEQUENCING The mission of the Next Generation Sequencing (NGS) Shared Resource of the Salk Cancer Center (SCC) is to provide integrated state-of-the-art genomics support for cancer research spanning basic and translational science. NGS members work with investigators on the design, conduct, analysis, and reporting of cancer research. SCC recruited Elsa Molina, PhD, as NGS Director with support from the SCC Deputy Director for Translation Ronald EvansIMT as Faculty Supervisor. During the current grant period, 29 SCC members utilized the NGS, resulting directly in more than 67 publications. The mission of the Next Generation Sequencing (NGS) Shared Resource is to facilitate cutting-edge genomics research at the Salk Institute by: 1) Providing cost-effective, rapid high-throughput, and state-of-the-art genomics instrumentation and services 2) Providing expert assistance and custom solutions in study design 3) Preparing sequencing libraries, including bulk and single-cell, and performing quality control to ensure that high-quality data are extracted from each experimental sample 4) Providing digital gene expression assay services 5) Providing whole tissue spatial transcriptomics services 6) Developing novel methods to enable cutting edge genomics technologies The NGS Shared Resource is committed to bringing novel genomics technologies to its core as well as embracing new and specific skills to best help SCC investigators with their research needs to successfully achieve their research goal.