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NIHNATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASESU54

RARE and Atypical Diabetes Network(RADIANT)

Active
Institution
Baylor College of Medicine, TX
Principal investigator
Ashok Balasubramanyam
Funding
$983K
Duration
2018–2029
Open portfolio

Moonbase score

Still being scored

Abstract

ADMINISTRATIVE CORE – PROJECT SUMMARY/ABSTRACT The Administrative Core is to further RADIANT goals by managing RADIANT resources and demonstrating leadership to RADIANT committees and special interest groups. RADIANT has an administrative committee structure and a scientific committee structure. Committee leadership, membership and overall responsibilities are approved by the Steering Committee. Committee chairs are appointed for a minimum term of 1 year at which point they will be reassessed by the Steering Committee to ensure committee objectives and goals are being reached. Administrative committees focus on protocol operations and are overseen by the Steering Committee. The following are the administrative committees: Coordinators, Recruitment and Retention, Protocol Oversight (previously Protocol Implementation), and Laboratory Implementation. Scientific committees are focused on the identification of rare and atypical forms of diabetes (Adjudication Committee, Discovery Team, Publications and Presentations), Ancillary Studies/Data Access, and the analysis of accumulating data (Special Interest Groups (SIG)) to ensure comprehensive oversight of study outcomes, additional scientific discovery (e.g., deeper phenotyping) and data analysis. 14 SIGs have been established thus far to focus on next steps for phenotypic cohorts, cases with promising genetic variants, and genome exploration. The Administrative Core also oversees the design and implementation of the RADIANT website. The RADIANT DCC continues to expand and implement the RADIANT platform, an enterprise level web-based portal for the RADIANT network which provides applications and services that enables users to identify, screen, enroll, and collect data from individuals with atypical diabetes, as well as store, manage, analyze, and share those data. The system also includes applications for specimen collection, tracking, laboratory results and analysis, adverse events tracking, reporting, data compliance, and study staff and committee communications and collaboration.

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U54NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASESZDK1-GRB-9diabetessteeringcommitteeoversightatypicalcommitteessteering committeeprotocol

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