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NOBEL PRIZE 2026

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NIHNATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES

NMR Core

Active
Institution
UNIVERSITY OF PITTSBURGH AT PITTSBURGH, PA
Principal investigator
Angela M. Gronenborn
Funding
$561K
Duration
2022–2027
Open portfolio

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Abstract

NMR Core The overall goal of the NMR Core is to provide state-of-the art capabilities for PCHPI researchers, for atomic- level characterization of structure and dynamics of HIV-1 proteins and their complexes. To accomplish this goal, we will take advantage of superb instrumentation resources, innovative experimental protocols, and unique expertise developed during the past decade. Specific aims are designed to i) support PCHPI projects and extra- center collaborators by providing cutting-edge solid-state NMR capabilities for HIV-1 research, and ii) develop in-cell solution and solid state 19F NMR for HIV-1 research. The novel technologies developed by the NMR Core will have major impact on HIV-1 cellular structural biology.

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NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASESU54ZAI1-JBS-Aunique expertisetechnologies developedsuperbatomic levelhiv-nmraims designedresearch novel

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