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NOBEL PRIZE 2026

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NIHNATIONAL CANCER INSTITUTE

Project 2

Active
Institution
Stanford University, CA
Principal investigator
David H Rehkopf
Funding
$338K
Duration
2023–2028
Open portfolio

Moonbase score

Still being scored

Abstract

Research Project 2: Project Summary Despite some successes of individual-level programs and interventions to promote behaviors that prevent colorectal cancer – the burden in persistent poverty areas remains particularly high. Many experts in cancer prevention and control have recently argued that to truly address this burden we must take a multilevel approach that includes addressing the causes of cancer. We propose a quasi-experimental study of the impacts of the largest anti-poverty policy program for families in the U.S. – the Earned Income Tax Credit (EITC), with a particular focus on local persistent poverty areas in two counties in California: 1) Yolo, a largely agricultural county which is home to University of California, Davis (UCD), and the county with the highest poverty rate in California; and 2) Santa Clara, an urban area home to Stanford University. Since 2015, for households earning up to $30,000 per year, the California EITC (CalEITC) and Federal Credits provide up to $10,000 a year. This amount of income, through helping pay for daily expenses, food and housing, transportation, and healthcare, and therefore also by reducing the stress of poverty, may influence several risk factors for colorectal cancer. We will work with our Regional Coalition of community partners to accomplish the following specific aims: Aim 1. Examine the impact of the California 2015 EITC expansion (CalEITC) on colorectal cancer risk factors and preventative screening, Aim 2. Estimate the short-term effects of CalEITC on colorectal cancer risk factors and screening among Californians living in persistent-poverty areas, Aim 3. Qualitatively examine 3.1) CalEITC recipients’ experience to understand the impacts of CalEITC on behaviors and exposures related to colorectal cancer prevention, and 3.2) non-EITC recipients who qualify to understand the reasons for not applying for CalEITC benefits, and Aim 4. Work with our Regional Coalition to build capacity in support of multilevel interventions by estimating the effects of EITC expansion on reducing colorectal cancer incidence rates in persistent poverty areas. The project will build on the multiple institution and multi-disciplinary nature of the UPSTREAM Research Center to address the most pressing needs for cancer prevention in persistent poverty areas in Yolo and Santa Clara Counties. Through the case of the CalEITC, in coordination with the evaluation of Guaranteed Basic Income in Project 1, we expect that our program will add evidence to support advocacy and actions to promote colorectal cancer prevention and screening.

LOADING MOONBASE SCORE

NATIONAL CANCER INSTITUTEU54ZCA1-SRB-2californiacoalitioncolorectal cancerpovertycancer preventionsantapersistent povertycolorectal

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