ANNOUNCEMENT

NOBEL PRIZE 2026

This year's laureates, their fields, and the discoveries that earned them the prize.Live nowSee the winners
Moonbase
← Back to Awards
NIHNATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES

Human Immune Monitoring Core

Active
Institution
Stanford University, CA
Principal investigator
Holden T. Maecker
Funding
$137K
Duration
2022–2027
Open portfolio

Moonbase score

Still being scored

Abstract

ABSTRACT – Human Immune Monitoring Core The Human Immune Monitoring Core will support the Stanford HIPC projects with standardized, state-of-the- art, comprehensive immune monitoring services for the clinical samples collected across all three clinical studies in this application. The Core will leverage the considerable infrastructure of the Human Immune Monitoring Center at Stanford, which has all the necessary space, equipment, expertise, and personnel to conduct these assays. Specifically, the Core will provide: (1) Olink immunoassays on serum, using their inflammation panel of 92 cytokines and related molecules; (2) CyTOF PBMC phenotyping with intracellular cytokine staining (CyTOF ICS) and EpiTOF assays for DNA methylation in specific immune cell subsets; (3) BD Rhapsody single-cell transcriptomics assays with AbSeq and TCR targeting; and (4) Luminex assays for antibodies to SARS-CoV-2 proteins and antigens of other heterologous viruses. Data from these assays will be organized, mapped to clinical demographics, and shared with the Data Management and Analysis Core, using our Stanford Data Miner online database. This will also facilitate the upload of these data sets to ImmPort. We anticipate that the data generated through the Core will be a resource to be mined well beyond the limits of the HIPC grant.

LOADING MOONBASE SCORE

NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASESU19ZAI1-TC-Xcytofmonitoringimmuneassayshuman immunestanfordimmune monitoringics

Questions for Stanford University

Answered by the team behind this research.

No questions yet. Sign in to ask the first one

Related grants

Same researchers, same institution, same topic, scored first.