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NIHNATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCESR35

New Strategies in Catalytic Organic Synthesis with Organoboron Reagents

Active
Institution
Boston College, MA
Principal investigator
James Patrick Morken
Funding
$608K
Duration
2018–2028
Open portfolio

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Abstract

Project Summary. New functional group transformations can enable synthetic chemists to disconnect molecules in new ways, thereby enabling new synthesis strategies. Ideally such new technologies enable the synthesis of important molecules from untapped, perhaps more readily available, starting materials. The proposed research will extend our fruitful studies on catalytic diboration, catalytic cross-coupling, and catalytic boronate rearrangements to address important new stereoselective transformations. Our strategies are keenly focused on developing processes that are readily accessible to the end-user without specialized techniques, equipment, or materials.

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R35NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCESSpecial Emphasis Panel[ZRG1-BCMB-J(55)R]catalytictransformationsreadilysynthesisstereoselectivedisconnectcross-couplingreadily accessible

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