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NOBEL PRIZE 2026

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NIHNATIONAL INSTITUTE OF MENTAL HEALTH

Dopaminergic Gut-Brain Signaling on Adolescent Reward Learning After Adversity: Toward New, Noninvasive Treatments for Depression and Anxiety

Active
Institution
UNIVERSITY OF CALIFORNIA LOS ANGELES, CA
Principal investigator
Bridget L Callaghan
Funding
$662K
Duration
2024–2029
Open portfolio

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Abstract

ABSTRACT Approximately 2 in 10 American adolescents have experienced major depression in their lifespan, and 3 in 10 have experienced an anxiety disorder. Despite the clear

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NATIONAL INSTITUTE OF MENTAL HEALTHR01ZMH1-ERB-G(01)anxietydepressionexperiencedadversitydopaminergicmajor depressiongut-braindepression anxiety

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