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NOBEL PRIZE 2026

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NIHNATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISMK24

Advancing Couple and Family Alcohol Treatment through Patient-Oriented Research and Mentorship

Active
Institution
MEDICAL UNIVERSITY OF SOUTH CAROLINA, SC
Principal investigator
Julianne Christina Flanagan
Funding
$192K
Duration
2023–2028
Open portfolio

Moonbase score

Still being scored

Abstract

Alcohol misuse has a salient precipitous effect on intimate partner violence (IPV), which is a persistent public health crisis affecting approximately one-third of the U.S. population. Posttraumatic stress disorder (PTSD) is highly prevalent, has a clear causal effect on alcohol misuse, and it is a robust independent predictor of IPV. However, few studies have examined the combined effects of PTSD and alcohol misuse on IPV. This question is critical to address because effective prevention and treatment approaches for alcohol-related IPV are scant. Integrating these two siloed areas of the literature can help inform the development of novel, trauma-informed modalities for couples to produce stronger and more sustainable outcomes. Dr. Flanagan is the ideal candidate to advance the clinical science in this area. Under the proposed mid-career development award, she will accelerate her thriving patient-oriented alcohol research program by enhancing her skills with 1) oral alcohol administration, 2) intensive ambulatory assessment, and 3) psychophysiology. She will achieve these goals through expert consultation, didactic training, and implementation of the proposed research project. Her team will examine the combined effects of alcohol misuse and PTSD on alcohol-related IPV among couples (N=70) in both a controlled laboratory setting and in naturalistic settings. The study, which was designed to complement mentees’ independent research interests, will also compare outcomes across settings and explore heart rate variability as a physiological mechanism underlying the hypothesized relations. The invaluable protected time and resources provided by this K24 will enable Dr. Flanagan to achieve her primary goal of expanding her mentoring availability and skillset at this pivotal mid-career stage. She will engage a program of didactics and expert coaching to amplify her investment in mentoring, leadership, and science. Achieving these synergistic objectives will accelerate the science of couple and family alcohol research and set the stage for innovative new dyadic treatments. This award will also ensure that Dr. Flanagan is equipped to support the next generation of enthusiastic new investigators and to ensure the longevity of this vital yet underrepresented area of the alcohol field.

LOADING MOONBASE SCORE

K24NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISMEpidemiology, Prevention and Behavior Research Study Section[AA-2]alcohol researchalcohol misusealcoholipvcombined effectsalcohol-relatedmisuseptsd

Questions for MEDICAL UNIVERSITY OF SOUTH CAROLINA

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