Illumina NovaSeq X Plus High Throughput DNA Sequencer for Emory University

PROJECT SUMMARY/ABSTRACT: The Emory National Primate Research Center Genomics Core (GenCore) is requesting support to acquire an Illumina NovaSeq X Plus Sequencing System. Since 2011, the EPC Genomics Core has served a diverse collection of EPC and Emory University investigators; assisted in planning, preparing, and executing projects having dynamic deep-sequencing needs. From the characterization of genome-wide DNA methylation profiles in the context of neurodegeneration, to identifying differentially expressed genes following various vaccination regimens, the GenCore has worked closely with investigators to successfully meet the demands of their research programs. Over the past several years, massively parallel deep sequencing has made significant contributions to biomedical research– particularly due to increased affordability and practicality over more conventional approaches to gene sequence and expression characterization. Our growing user base, and the increased sophistication of our users' needs, requires the GenCore to replace our existing Illumina NovaSeq 6000 with the NovaSeq X Plus, which will decrease turn-around time, decrease sequencing costs, and increase the volume of samples that can be sequenced simultaneously. The NovaSeq X Plus will bring genome-center capabilities to the EPC GenCore– investigators will have in-house access to genome-scale deep sequencing services with corresponding informatics support. Our users, minor and major, correspond to investigators leading their field, and supporting their evolving sequencing needs by acquiring an Illumina NovaSeq X Plus will undoubtedly benefit the larger scientific community.