IDeA National Resource for Quantitative Proteomics

Abstract Since 2020, the IDeA National Resource for Quantitative Proteomics has operated as a NIGMS R24 National Resource in support of NIH-funded investigators, and other academic researchers and qualified scientists across the United States, by providing the most cost-effective access to state-of-the-art proteomics platforms and supporting a substantial nation-wide biomedical research community with unique education, outreach, and training opportunities. In this renewal, we seek to build on the high level of success during the current funding cycle by expanding access to and opportunities in service, education, outreach, and training for quantitative proteomics to a growing nation-wide userbase. Our intent is to provide broad access to investigators without regard to the specific biomedical focus of their research, while not duplicating or replacing resources supported by NIH or host institutions. With robust institutional support, we will use best-in-class practices to enable user access to the next generation of liquid chromatography-coupled mass spectrometry systems and skilled staff for data collection and analysis. We will make our capabilities and abilities broadly known to the nation-wide biomedical research community through advertisement, education, and outreach. The goals of the IDeA National Resource for Quantitative Proteomics are to provide unmatched and most cost-effective access to state-of-the- art quantitative proteomics platforms and education, outreach, and training opportunities that will increase the capacity of NIH-funded investigators, and others in academic laboratories across the United States, to perform cutting-edge biomedical research. By pursuing our goals, we will support the biomedical research mission of NIH for both fundamental and translational research focused on human diseases including cancer. We will pursue the following Specific Aims to accomplish our goals: (1) Provide state-of-the-art proteomics services to a nation- wide userbase, (2) Provide educational opportunities for quantitative proteomics to a nation-wide userbase, and (3) Provide outreach and training for quantitative proteomics to a nation-wide userbase.