OpenNeuro: An open archive for analysis and sharing of BRAIN Initiative data

Project Summary/Abstract The BRAIN Initiative is supporting a broad portfolio of neuroscience research aimed at revolutionizing our understanding of the brain. The sharing of data obtained from this research is critical both to leveraging this major public investment and to ensuring the rigor and reproducibility of NIH-funded research. We propose a renewal of support for the OpenNeuro data archive, which provides a platform for the storage, processing, and sharing of neuroimaging data collected as part of the BRAIN Initiative. OpenNeuro enables researchers to easily share a broad range of neuroscience data types, based on the Brain Imaging Data Structure standard for organizing datasets. The platform shares data openly and provides researchers with several avenues to access and reuse the data. In the renewal period we propose to continue supporting a high level of performance for the archive, and to extend the work done in the initial grant period. First, we will provide a specialized portal for BRAIN Initiative investigators, which will help more clearly link their research to funding sources, and to provide them with the ability to more flexibly select an appropriate data use agreement. We will also implement enhanced user profiles, linking shared datasets to standard researcher identities through the ORCID system. Second, we will enhance the ability to search for datasets by improving the ability for researchers to specify metadata that is linked to standard ontologies. Third, will improve the reusability of OpenNeuro datasets by providing support for the sharing of derivative data as well as statistical models, and by providing preprocessed data and quality control reports. Together, these improvements will sustain the success of the OpenNeuro archive and provide neuroscientists with increasingly usable data to address fundamental problems of brain function and health.