ANNOUNCEMENT

NOBEL PRIZE 2026

This year's laureates, their fields, and the discoveries that earned them the prize.Live nowSee the winners
Moonbase
← Back to Awards
NIHNATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASESR01

Inhibition of regeneration restraining pathways to promote healing

Active
Institution
Johns Hopkins University, MD
Principal investigator
Luis Andres Garza
Funding
$649K
Duration
2025–2030
Open portfolio

Moonbase score

Still being scored

Abstract

Project Summary Abstract The long term objective of the proposed research is to enhance healing after injury that is often slow and incomplete. We hypothesized that injury to epithelial tissue like skin and gut share commonalities in healing, with some native injury responses which actually restrain healing. The goal of this grant is to define the mechanism of this restraint in hopes of developing therapies to enhance healing. We will test if inhibition of these pathways that restrain healing can improve regeneration after injury or infection to the gut or skin in the hopes of suggesting a new class of therapeutics to aid healing from diverse injuries.

LOADING MOONBASE SCORE

R01NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASESSpecial Emphasis Panel[ZRG1 MSOS-K (02)]injuryregenerationcommonalitiesguthealingskinhopespathways promote

Questions for Johns Hopkins University

Answered by the team behind this research.

No questions yet. Sign in to ask the first one

Related grants

Same researchers, same institution, same topic, scored first.