ANNOUNCEMENT

NOBEL PRIZE 2026

This year's laureates, their fields, and the discoveries that earned them the prize.Live nowSee the winners
Moonbase
← Back to Awards
NIHNATIONAL INSTITUTE OF MENTAL HEALTH

Digital Delivery of Evidence-Based Mental Health Content and Mentoring to Adolescents

Active
Institution
APPA HEALTH INC, CA
Principal investigator
Christopher Williams
Funding
$623K
Duration
2023–2027

Moonbase score

Still being scored

Abstract

PROJECT SUMMARY. This Direct-to-Phase II SBIR proposal will study Appa Health, a smartphone and computer-based mental health application for adolescents. Appa combines (1) delivery of concise, evidence-based mental health skills via engaging educational videos informed by Cognitive Behavioral Therapy, and (2) trained, supervised mentors with relatable, non-clinical backgrounds who provide structured guidance to facilitate adolescents’ engagement with digital content. According to Appa’s theory of change, mentorship supports adolescent well-being both directly (through emotional and practical support) and indirectly (by encouraging use of core skills like cognitive restructuring and behavioral activation). The study will assess the effectiveness and cost-efficiency of the full Appa experience compared to a digital-only version and a waitlist control. A pilot (N=75) will inform procedures and retention strategies, followed by a randomized clinical trial (N=400) evaluating outcomes on depression, anxiety, well-being, and user engagement. The project addresses the national mental health workforce shortage by testing a model that integrates non-clinical guidance with expert-designed digital content. Appa's innovation lies in combining accessible mentoring with youth-oriented video delivery formats to increase engagement with evidence-based strategies. The study will also inform Appa’s commercialization efforts, particularly in education and employer markets seeking scalable, outcome-driven mental health tools. Cost-effectiveness analysis will guide product design and service delivery strategies.

Research team

  • Michelle R. KaufmanPI
  • Christopher WilliamsPI

LOADING MOONBASE SCORE

NATIONAL INSTITUTE OF MENTAL HEALTHR44Special Emphasis Panel[ZRG1-SCIL-D(10)B]mentaladolescentsdigitalcontentmental healthevidence-basednon-clinicaldelivery

Questions for Appa Health Inc

Appa Health Inc hasn't set up its Moonbase portfolio yet, so questions about this research can't be asked here.

Same researchers, same topic, scored first.