Molecular Imaging in Cancer Biology Training Program

PROJECT ABSTRACT The central mission of the T32 “Molecular Imaging in Cancer Biology” program (T32 MICB) will be to develop novel molecular imaging methods, technologies, and platforms that will accelerate the understanding of human cancer biology as a basis for designing curative cancer therapeutic regimens as well as cutting-edge diagnostic, prognostic, and therapeutic tools. This overall goal will be achieved under the auspices of three key themes: (1) “Imaging Fundamental Biology,” (2) “Imaging New Model Systems,” and (3) “Imaging Technology Development.” This T32 MICB research portfolio is situated at the intersection of various disciplines—from basic science including chemistry and physics, structural biology, drug development, cell biology, and developmental biology to cancer biology, invasion and metastasis, and applied disciplines, including pharmacology, nanotechnology, radiochemistry, engineering, and medicine. Fundamental knowledge about the biology of cancer has burgeoned, but the translation of basic science discoveries to clinical advancements can be slow and inefficient; molecular imaging can significantly accelerate this process and a well-trained population of basic scientists well-versed in all aspects of molecular imaging is crucial to the success of this endeavor. The faculty preceptors chosen for this T32 MICB reflect the broad range of expertise and are leaders in their respective imaging fields. They are well-funded and have independent R01 (cancer-related) or R01-like research support (e.g., R35 or HHMI). To ensure that the trainees (five post-doctoral slots and one pre-doctoral slot per year) have a full well-rounded training experience (including resilience and well-being) in preparation for independent careers, our initial design is based on a three-year training program for both the postdoctoral fellows and the predoctoral graduate student trainees. Prior to entry into the T32 MICB program and during the program, the trainees will be informed about the mission of the T32 MICB program, which is to produce scientists with specialized knowledge in advances in cancer biology and imaging technology, within a culture of respect and engagement. Furthermore, trainees will be informed about expected achievements during the program and that their progress will be continuously evaluated and benchmarked.