UofL RBL Pandemic Preparedness and Response Integrated Research Core

SUMMARY: PANDEMIC PREPAREDNESS AND RESPONSE INTEGRATED RESEARCH SERVICES CORE The Pandemic Preparedness and Response Integrated Research Services Core (PaPR Core) shall support all Risk Group 3 (RG3) pathogen studies conducted at the University of Louisville (UofL) Regional Biocontainment Laboratory (RBL). In alignment with the NIAID Pandemic Preparedness Mission, the PaPR Core shall serve investigators at UofL, our regional academic and industrial partners, collaborating investigators in the NBL/RBL network and other investigators who wish to avail of our facilities and expertise. The PaPR Core supports funded research programs by providing scientific expertise on study design, labor to support execution of both in vitro and in vivo BSL-3 studies, and data analysis and interpretation services that culminate in issuing a comprehensive study report to the sponsor investigator. The PaPR Core shall operate on a cost-recovery business model, with revenue re-invested in core services. The aims of the PaPR Core are to: (1) Support continuous refinement of RG3 pathogen infection models established at UofL RBL.; (2) Support continuous refinement of RG3 pathogen infection models established at UofL RBL; (3) Enable investigations on the impact of aging and chronic metabolic disease on RG3 pathogen infections; and (4) Enable studies on the impact of environmental toxicant exposure on RG3 pathogen infections.