Yale-SCORE Resource Support Core

RESOURCE SUPPORT CORE ABSTRACT The main objective of the Resource Support Core is to provide essential research-related resources to Yale- SCORE investigators, trainees, and collaborating researchers. The resources provided will serve to maximize the quality of the data, the comparability of data across Projects, and to increase dynamic communication among Yale-SCORE researchers to ensure the translation of results across projects and within the greater research environment. The Core will: 1) Provide expert consultation, management, and coordination of IRB/IACUC approvals, regulatory procedures and data safety monitoring, as required for animal and human Projects and Pilots; 2) generate comprehensive strategies to recruit equal numbers of females and males in samples of human subjects into all Yale-SCORE clinical studies and ensure that equal numbers of female and male animals are studied in preclinical projects; 3) provide data management and analytical techniques that incorporate state-of-the-art SABV approaches across the conceptualization, methods, analysis, and reporting of all Yale-SCORE findings; 4) provide centralized training and quality control of core assessments and assays across animal and human studies to maximize the scientific yield across studies; 5) provide expertise to mine national and international big data sources with computational and machine learning approaches, to expand our focus on sex differences in alcohol science across the lifespan; 6) and, provide access to large recovery communities for research opportunities.