P30-Core Grant for Vision Research Core C

The overall goals of the Biostatistics and Bioinformatics (Bioanalysis) Core are to improve the quality, and increase the quantity of research conducted by NEI-R01 holders in the Atlanta (AVRC). This is done through better and faster biostatistics and informatics approaches than those that the typical PI can conduct by himself without Core support. The Bioanalysis staff benefits from formal rigorous mathematical training in biostatistics and informatics for interpretation of experimental results, so that NEI-R01 PIs do not need as much biostatistics and informatics training to effectively design experiments and interpret results. The Bioanalysis Core: 1. Provides better resources and more convenient access to state of the art analysis tools than an NEIR01 PI could provide or support alone. 2. Consults with PIs to determine scope of a project, timeframe, services needed. 3. Conducts work that would otherwise require hiring of bioinformatics and biostatistics experts that is impractical for an R01 budget. 4. Provides training to PIs and personnel as appropriate for more routine tasks. 5. Pre-tests and troubleshoots data and software from bleeding edge technologies to avoid repeated mistakes by multiple individual PIs. These Aims serve to maximize the utility of each R01 experiment and enables experiments that otherwise could not be conducted or analyzed. The Bioanalysis Core leverages and facilitates usage of university level resources and talents from among the five institutions that make up the AVRC.