Administrative Core

ADMINISTRATIVE CORE PROJECT SUMMARY The overall goal of the Administrative Core is to provide direction, guidance, and oversight for the PCEN and assure its effective and efficient functioning. The Administrative Core will facilitate the work of the two Biomedical Research Cores, the Learning Health System Core (LHS Core) and the Molecular Precision Nephrology Core (MPNC), and support the Enrichment Program, Opportunity Pool Pilot and Feasibility Program, and two Research Projects. The Enrichment Program aims to equip the research base with additional skill sets and maximizes interactions and intellectual discourse within the PCEN. Initiatives within the Enrichment Program will encourage and support innovative multidisciplinary research in pediatric kidney disease through early career engagement, including the Summer Scholar program; career development and collaborations; and patient, family, and community engagement. The Opportunity Pool Pilot and Feasibility Programwill continue to stimulate and solicit new project ideas to address key barriers to research progress in pediatric nephrology, specifically for early stage investigators, new investigators, or established investigators not previously involved in research on pediatric kidney disease. The CHOP PCEN organizational structure includes oversight by an External Advisory Board (EAB) and input and guidance from a Scientific Advisory Committee (SAC). The Steering Committee will set overall policy for the CHOP PCEN and will include the Center Co-Directors, the SAC Chair, the Biomedical Core Directors and leadership, and the ProgramLeads. In addition to facilitating collaborations across the CHOP PCEN collaborators at CHOP, the University of Pennsylvania, and Johns Hopkins University, the Administrative Core will support interdisciplinary partnerships across the CHOP PCEN research base and the PCEN Network. Our team includes individuals with proven track records in mentoring, basic science, translational research, clinical investigation, epidemiology, informatics, and health services research. We will build upon the success of our established PCEN to expand the evidence base of observational data for clinical trial design and enhance the infrastructure for pragmatic clinical trials and comparative effectiveness through the LHS Core; facilitate the identification of novel therapeutic targets through the MPNC; foster collaboration in kidney disease research across other centers; and mentor members of the broader nephrology community by supporting the Enrichment Program, an Opportunity Pool Program, and innovative research projects in childhood kidney disease.