NYU-CUNY Prevention Research Center - Revision - 5- 24-003

Project Summary/Abstract The New York City (NYC) Cancer Prevention and Control Research Network Collaborating Center (CPCRN) builds on the multi-disciplinary expertise and community partner networks of the NYU-CUNY Prevention Research Center (PRC), including the City University of New York (CUNY) School of Public Health, the NYU Langone Health’s Department of Population Health, and NYU Langone Perlmutter Cancer Center, an NCI- designated Comprehensive Cancer Center. The goals of the NYC CPCRN are to employ social determinants of health (SDoH) strategies to reduce preventable cancers, increase early cancer screening and detection, and improve cancer equity among low-income, minoritized populations in urban areas. The technical assistance, training, and dissemination activities we offer are centered on participatory approaches, disaggregated data collection, cultural adaptation, and implementation of evidence-based cancer prevention and control strategies relevant to diverse, urban communities in place-based and clinical settings. For the five year period, we propose conducting two studies that will each leverage an established network of NYC community and clinical partners serving the Asian American, Black, Latine, and other understudied immigrant communities in order to reduce cancer disparities and improve cancer control. The first study is implementation evaluation to assess the factors that impact the reach, effectiveness, and adoption of clinical decision support and culturally and linguistically adapted materials to improve lung cancer screening rates among low-income, multi-ethnic communities in NYC. Using a participatory approach to engaging multiple stakeholders and diverse communities, we will apply RE- AIM and the Consolidated Framework for Implementation Research to evaluate, refine and optimize clinical- community strategies focused on improving lung cancer screening among Asian American, Black, Latine, and other understudied immigrant communities. We also propose a second formative research study, to inform a multi-level, healthcare provider intervention to improve human papilloma virus (HPV) vaccine rates among high- risk and understudied communities in NYC, specifically Arab- and Mexican American. The proposed NYC CPCRN application is aligned with Healthy People 2030 cancer-related objectives to increase the proportion of adults who receive screening for lung cancer and to improve HPV vaccination rates. Research will focus on strengthening community-clinical linkage models, employing CHW strategies for cancer patient navigation, and tackling SDoH to reduce cancer disparities and advance equity. The NYC CPCRN will also continue to actively engage and collaborate with partners across the network in joint work and interest group activities.