Core C- Biostatistics and Data Analysis Core
- Institution
- University of Pennsylvania, PA
- Principal investigator
- Adam Christian Naj
- Funding
- $877K
- Duration
- 2016–2026
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Abstract
Core C Project Summary Core C (Quality Control/Quality Assurance and Statistical Analysis Core) primary focuses on a) the development, implementation, and validation of “best practices” at all steps of the GCAD data production activities; and b) the planning and performance of association meta-analyses combining ADSP and non-ADSP datasets. Specific Aims are: (1) Evaluate variant quality differences between original and updated calling pipelines; (2) Develop/Extend Quality Control/Quality Assurance (QC/QA) Pipelines; (3) Quality Assurance of ADES+ADSP Sequencing Joint Calling and Association Analysis; (4) Quality Assurance of of TOPMed+ADSP Sequence Joint Calling and Association Analysis; (5) Developing/Extending SV Calling best practices for ADSP sequencing data.
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