Administrative Core

ADMINISTRATIVE CORE Abstract The administrative core will lead, manage, and support all activities of the Acquired Resistance to Therapy Network (ARTNet) Center for Pancreatic Cancer (ACPC). It will represent ACPC at the trans-ARTNet network activities, and in interactions with NCI. The ARTNet administrative core will be responsible for managing the activities of the synergistic research ACPC projects with scientific and technical expertise and resources in the areas of therapy resistance, signaling, metabolism, pancreatic cancer biology, organoid and mouse models, immune and non-immune stroma, and PDAC tissues for studying the acquired therapy resistance in cancer. The core leadership will provide expertise spanning the basic to translational spectrum, consistent with the overarching theme of ACPC, with track records of building and guiding large scientific teams to successfully advance fields in transformative ways. We will utilize strategic management with innovative approaches, including an educational component to bring new talent into the field, engage diverse teams to facilitate new ideas, leverage national talent pertinent to the proposed goals, engage university leadership in building support for cutting-edge science, and utilize dedicated university expertise to facilitate engagement with basic and translational research programs to grow ARTNet centric interests. The administrative core will provide support for personnel involved in the administration, coordination, communication, biostatistics, and bioinformatics to support the ARTNet activities within the center and campus, other ARTNet centers, ARTNet Coordinating Data and Management Center (CDMC) and National Cancer Institutes (NCI). The administrative core will also provide scientific oversight, result dissemination, budgetary oversight, and clerical functions associated with the overall research program in this ACPC application. The core will implement center-wide activities which include, developing new collaborations on the ACPC projects, organize annual retreat, support acquired cancer therapy resistance seminar speakers within various academic units, advocate for the next generation of scientists (graduate students, postdoctoral researchers, and junior faculty) in the ACPC member laboratories. Finally, the administrative core will represent ACPC on the ARTNet steering committee.