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NOBEL PRIZE 2026

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NIHEUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT

Restoring complex movement and locomotion after paralysis through collaborative copilots

Active
Institution
UNIVERSITY OF CALIFORNIA LOS ANGELES, CA
Principal investigator
Jonathan Chau-Yan Kao
Funding
$1.1M
Duration
2025–2030
Open portfolio

Moonbase score

Still being scored

Abstract

PROJECT SUMMARY There are no widespread devices available that significantly improve the quality of life for those with paralysis. A widespread and effective device for paralysis should be low risk, yet high performance, enabling complex movements needed to perform everyday tasks. We propose to achieve a low risk, high performance device through three thrusts. Our first thrust is to capitalize on advances in artificial intelligence (AI) that enable us to train robots that perform the same types of tasks that humans perform, including folding laundry, putting food in a pan, opening door knobs, or picking up a bag of chips. Because robots can perform these tasks, we reason that as long as an AI copilot can infer a human's goal to perform a certain movement, the copilot can then help perform the complex movements associated with the task. We achieve this by training new copilot architectures that use computer vision, as well as non-invasive signals reflecting the user's intent, to perform complex actions. Our second thrust is to take advantage of and fuse many non-invasive signal sources, which together provide enough information for the copilot to infer the user's goal and help the user complete an action. Our third thrust is to develop methods to adapt the user and copilot as they share control. We hypothesize this will have a key impact on increasing system performance and robustness. We believe this proposed work, if successful, will have a transformative impact on the development of clinically viable devices that help people with paralysis move autonomously.

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EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENTDP1Special Emphasis Panel[ZRG1 MBBC-J (70)]inferperformparalysisthrustlow riskrobotsuserhigh performance

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