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NOBEL PRIZE 2026

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NIHNATIONAL INSTITUTE ON AGING

Transcriptomic Core

Active
Institution
COLUMBIA UNIVERSITY HEALTH SCIENCES, NY
Principal investigator
Peter Alan Sims
Funding
$415K
Duration
2010–2030
Open portfolio

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Abstract

PROJECT SUMMARY The Single Cell Analysis and Bioinformatics Core will provide state-of-the-art experimental technology, computational biology, and biostatistical support tailored specifically to the program project. This includes scalable, pooled-sample methodology for single-cell RNA-seq (scRNA-seq) and multi-modal single-cell analysis technologies for multiplexed lineage tracing and surface protein profiling (CITE-seq). The Core will also provide comprehensive bioinformatics support including data processing and specialized tools for dimensionality reduction and automated annotation of single-cell data. Finally, we will assist Project investigators with experimental design and statistical modeling across a variety of modalities including single-cell genomics, mass spectrometry, and indirect calorimetry.

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NATIONAL INSTITUTE ON AGINGP01Special Emphasis Panel[ZAG1 ZIJ-P (M2)]bioinformaticssingle-cell analysiscalorimetrysupport includingsingle-cellcite-seqsingle-cell datasurface protein

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