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NIHOFFICE OF THE DIRECTOR, NATIONAL INSTITUTES OF HEALTH

Resource Core

Active
Institution
Marine Biological Laboratory, MA
Principal investigator
Marko E Horb
Funding
$679K
Duration
2010–2030
Open portfolio

Moonbase score

Still being scored

Abstract

Project Summary – Core/Resource This project supports continued funding for the National Xenopus Resource (NXR) located at The Marine Biological Laboratory in Woods Hole, MA. The NXR is one of the top priorities for the Xenopus community. The NXR was established in 2010 to serve as a national resource for researchers working with the Xenopus amphibian model system, which includes two species Xenopus laevis and Xenopus tropicalis. The NXR also serves as a national repository for community-generated animal stocks as well as serving as an advanced training venue that greatly facilitates productivity for a multitude of researchers. It is a community-oriented resource center that serves all Xenopus researchers, including individuals from large research-focused universities to small liberal arts colleges. As biological research becomes ever more complex, often requiring specialized animal lines and involving diverse technologies, individual laboratory units become insufficient to meet all the demands required for addressing significant biological problems and a centralized repository or stock center becomes essential. The NXR will maintain current stocks of frogs as well as obtain new lines making them available to the community; this includes special inbred, wild type and mutant lines of both species. During this project period, we will improve the NXR website and link it with the Xenopus model organism database, Xenbase.

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OFFICE OF THE DIRECTOR, NATIONAL INSTITUTES OF HEALTHP40Special Emphasis Panel[ZRG1 MGG-F (55)]stocksresourcerepositorylinesresource projectxenopuswoods holefrogs

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