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NOBEL PRIZE 2026

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NIHNATIONAL INSTITUTE ON AGINGR01

Sense4Safety Intervention

Active
Institution
University of Pennsylvania, PA
Principal investigator
George Demiris
Funding
$614K
Duration
2025–2030
Open portfolio

Moonbase score

Still being scored

Abstract

Abstract Falls and fall-related injuries are significant public health issues for adults 65 years of age and older. Over a third of older adults (OA) fall each year and 10-20% of falls result in serious injuries such as fractures and head trauma. The annual direct medical costs in the US as a result of falls are estimated to exceed $50 billion, and this estimate does not include the indirect costs of disability, dependence, and decreased quality of life. This project targets community dwelling OA with mild cognitive impairment (MCI). MCI is a leading risk factor for falls in OA. Approximately 15%-20% of OA have MCI, and over 60% of OA with MCI fall annually – two to three times the rate of those without cognitive impairment. We have developed and pilot-tested an innovative technology-supported intervention called Sense4Safety to 1) identify escalating risk for falls real-time through in-home passive sensor monitoring; 2) employ machine learning to inform individualized alerts for fall risk; and 3) link `at risk' older adults with a coach who will guide them in implementing evidence-based individualized plans to reduce fall-risk. The purpose of this study is to assess the effectiveness of Sense4Safety in reducing fall risk with a randomized clinical trial, and understand implementation factors to improve the scalability of Sense4Safety in diverse community settings.

LOADING MOONBASE SCORE

R01NATIONAL INSTITUTE ON AGINGClinical Management in General Care Settings Study Section[CMGC]injuriesfallsolderindividualizedcognitive impairmentfall riskfallmci

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