The Stanford Clinical Center for the Study of Type 1 Diabetes in Acute Pancreatitis

PROJECT SUMMARY/ABSTRACT The Stanford Clinical Center (SCC) submits a renewal application to continue participation in the Type 1 Diabetes in Acute Pancreatitis Consortium (T1DAPC). The SCC will continue to recruit and retain participants into the signature prospective observational cohort study – the Diabetes RElated to Acute Pancreatitis and its Mechanisms (DREAM) study. The SCC will recruit into the optional arms of the study including the mixed meal tolerance test arm, the frequently-sampled intravenous glucose tolerance test arm, and the MRI imaging arm. The SCC will continue to work collaboratively to pursue the comprehensive immunological analyses planned upon DREAM cohort completion. In anticipation that DREAM enrollment will be completed in the next grant period, the SCC has assembled a multi- disciplinary team including the disciplines of pancreatology, endocrinology, radiology, and immunology to develop and complete current and forthcoming secondary and ancillary study proposals approved by the T1DAPC Steering Committee.