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NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASESNIH · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASESNIH

Advanced Development of a Multivalent Vaccine Candidate for Lassa Fever

Sundberg, Maja (Contact)·Thomas Jefferson University, PA·2017–2027·ACTIVE
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INSTITUTION

Thomas Jefferson University, PA

PRINCIPAL INVESTIGATOR

Sundberg, Maja (Contact)

FUNDING

$3.3M

YEAR

2017

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Abstract

To support advanced development of a multivalent vaccine candidates for Filovirus and Lassa Fever. This contract spans formulation and manufacture of the individual vaccine components, as well as stability testing, nonclinical immunogenicity and efficacy testing in nonhuman primates, IND enabling GLP repeated dose toxicology, and submission of an IND. The project is currently supporting a Phase I clinical trial to evaluate the candidate vaccine.

NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASESN01candidatephaseevaluateindividualtoxicologyclinicaladvancedsupportingformulationcomponentsdevelopmentnonclinicalfilovirusprimateslassamanufacture

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