KF Supplement -- Sustainable and Optimized Cloud Resources on behalf of the Kids First DRC

PROJECT SUMMARY/ABSTRACT The Kids First Data Resource Center (DRC) supports the development and deployment of cloud-based data resources spanning >1,200,000 files across >30,000 participants. Beyond its dbGaP-integrated cloud storage framework for data distribution, the DRC leverages AWS cloud-based resources that support a combination of storage, computation, and cloud services resources that provide for a number of key functionalities of the DRC including its data operations and harmonization framework, Portal data exploration/analysis features, CAVATICA, PedcBioportal, and FHIR services. Under the proposed supplement the DRC will continue to support the AWS cloud management resources for Kids First as well as support the transition and management of AWS storage and resources as required to additional NIH-approved environments, ensuring continuity and sustainability of cloud resources and services on behalf of the Kids First Program.