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NIHNATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES

NIAID VIROLOGY QUALITY ASSURANCE (VQA)

Completed
Institution
Duke University, NC
Principal investigator
Thomas Denny
Funding
$3.4M
Duration
2025–2026
Open portfolio

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Abstract

The purpose of the NIAID Virology Quality Assurance (VQA) program is to provide a comprehensive quality assessment program for virologic assays for HIV, and other viral pathogens, performed on samples from subjects enrolled in NIAID-sponsored multisite clinical studies. The VQA program ensures the validity and inter- and intra-laboratory comparability of virologic laboratory data obtained from NIAID-supported clinical trials and HIV natural history studies by providing laboratories with proficiency testing panels and real-time assay run controls and analyzing proficiency panel and assay run data from each laboratory. The VQA program also implements standards of performance for existing and state-of-the-art new virologic assays, develops and tests biostatistical methods relating to the assays, and acquires, tests, stores and dispenses quality control materials and reagents.

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NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASESN01proficiencyniaidassaysvirologyquality assurancerunassurancevirologic

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