Ultrafast Dynamic contract optical coherence tomography for high-throughput anti-cancer drug screening
- Institution
- University of Oklahoma Norman Campus, OK
- Principal investigator
- Yuye Ling
- Funding
- $203K
- Duration
- 2025–2026
Moonbase score
Still being scored
Abstract
Improving the success rate of oncology drug development requires pre ... clinical models that better mimic in vivo tumor environments and advanced imaging tools capable of real-time monitoring of treatment responses. Tumor organoids represent a biologically relevant 3D cancer model, yet existing imaging platforms fall short in achieving both high temporal resolution and high throughput. To address this critical gap, we propose to develop an ultrafast Dynamic Contrast Optical Coherence Tomography (DyC-OCT) system empowered by artificial intelligence (Al) for label-free, high-throughput 4D imaging of tumor organoids.
LOADING MOONBASE SCORE
Questions for University of Oklahoma Norman Campus
Answered by the team behind this research.
No questions yet. Sign in to ask the first one
Related grants
Same institution, same topic, scored first.
- NIH · University of Oklahoma Norman Campus66
Normalizing aberrant metabolism in ovarian cancer by a unique drug delivery system
Resham Bhattacharya · $367K · 2021–2026
- NIH · University of Oklahoma Norman Campus60
Exploiting gold nanoparticle as a probe to identify therapeutic targets
Resham Bhattacharya · $355K · 2021–2027
- NIH · University of Oklahoma Norman Campus58
Proteomics Core
Michael T Kinter · $250K · 2001–2030