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NIAID Investigator Initiated Program Project Applications (P01 Clinical Trial Not Allowed)

Posted May 7, 2026·open

AGENCY

HHS-NIH11

PROGRAM

Discretionary

AMOUNT

CLOSES

May 25, 2029

Description

This notice of funding opportunity (NOFO) invites submission of investigator-initiated Program Project (P01) applications. The proposed Programs should address scientific areas relevant to the NIAID mission including: biology and pathogenesis of infectious microbes, including HIV; host-microbe interactions; mechanisms regulating immune system development and function across the lifespan, and in response to infectious pathogens; immune dysfunction resulting in allergy, asthma, autoimmunity, immunodeficiency, or transplant rejection; and translational research to develop vaccines, therapeutics, and diagnostics to prevent and treat infectious and immune-mediated diseases. Each application submitted to this NOFO must include at least two related, synergistic Research Projects that share a common central theme, focus, and/or overall objective; and an Administrative Core. An application may include Scientific Core(s), if needed for the proposed research.

Eligibility

For profit organizations other than small businesses; Others (see text field entitled "Additional Information on Eligibility" for clarification); City or township governments; County governments; Native American tribal organizations (other than Federally recognized tribal governments); Special district governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Public housing authorities/Indian housing authorities; Public and State controlled institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; State governments; Native American tribal governments (Federally recognized); Independent school districts; Private institutions of higher education

Contact

National Institutes of Health

NIAID_P01_NOFO@mail.nih.gov

301-402-2541

Additional details

Funding instrument
Grant
Cost sharing required
No
Archived
Jul 24, 2029

Opportunity number: PAR-27-082

Search this number on Grants.gov for the official listing.