Grants.govNational Institutes of Health

Seed Instrumentation Support (SIS) Program (S10 Clinical Trial Not Allowed)

Posted Jun 25, 2026·open

AGENCY

HHS-NIH11

PROGRAM

Discretionary

AMOUNT

$50K – $400K

CLOSES

Jul 1, 2028

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Description

This Notice of Funding Opportunity (NOFO) aims to build new research capacity and develop a sustainable research program by supporting the purchase of a single commercially available biomedical research instrument currently unavailable in the institution. Instruments funded through this program must be shared among the users to create new research opportunities, enable reproducible data generation, encourage collaborative research and training, and strengthen long-term research capabilities. The minimum award is $50,000. While there is no limit on the total cost of the instrument, the maximum award is $400,000.

Eligibility

Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Independent school districts; Public housing authorities/Indian housing authorities; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); City or township governments; County governments; Native American tribal governments (Federally recognized); Private institutions of higher education; Public and State controlled institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Small businesses; Special district governments; State governments; For profit organizations other than small businesses

Contact

National Institutes of Health

odsig@mail.nih.gov

301-402-2541

Additional details

Funding instrument: Grant
Cost sharing required: No
Archived: Sep 1, 2028

Opportunity number: PAR-27-021

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