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Grants.govNational Institutes of Health

Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed)

Posted Jun 25, 2026·open

AGENCY

HHS-NIH11

PROGRAM

Discretionary

AMOUNT

$300K – $5.0M

CLOSES

Jul 1, 2028

Description

This Notice of Funding Opportunity (NOFO) announces the restructured Shared Instrumentation Grant (SIG) Program that consolidates three existing shared-use instrumentation programs, i.e., the Shared Instrumentation Grant program, the High-End Instrumentation Grant program, and the Basic Instrumentation Grant program. The NOFO invites applications from groups of NIH-supported investigators to purchase or upgrade a single state-of-the-art commercially available instrument or an integrated instrumentation system. The instruments purchased through the SIG Program are required to be optimally shared among the users to ensure efficient and cost-effective research operations, enable rigorous and reproducible measurements, and encourage collaborative research and benefit broad research communities at large. The minimum award is $300,000. There is no cap on the total cost of the instrument; however, the maximum award is $5,000,000. Cost sharing is required for premium instruments or special use instruments.

Eligibility

Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Public and State controlled institutions of higher education; State governments; Native American tribal governments (Federally recognized); County governments; Public housing authorities/Indian housing authorities; Native American tribal organizations (other than Federally recognized tribal governments); City or township governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Small businesses; Special district governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); For profit organizations other than small businesses; Independent school districts

Contact

National Institutes of Health

odsig@mail.nih.gov

301-402-2541

Additional details

Funding instrument
Grant
Cost sharing required
No
Archived
Aug 30, 2028

Opportunity number: PAR-27-022

Search this number on Grants.gov for the official listing.