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Grants.govNational Institutes of Health

NIH Director’s Pioneer Award (DP1 Clinical Trial Optional)

Posted Jun 29, 2026·open

AGENCY

HHS-NIH11

PROGRAM

Discretionary

AMOUNT

$700K – $700K

CLOSES

Sep 9, 2026

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Description

The NIH Director"s Pioneer Award supports individual scientists of exceptional creativity who propose bold and highly innovative research projects with the potential to produce a major impact on broad, important areas relevant to the mission of NIH. To be considered pioneering, the proposed research must reflect substantially different scientific directions from those already being pursued in the investigator"s research program or elsewhere. Applications in all topics relevant to the broad mission of NIH are welcome. Research may involve basic, translational, or clinical research. The NIH Director"s Pioneer Award is a component of the High-Risk, High-Reward Research (HRHR) program of the NIH Common Fund.

Eligibility

Public housing authorities/Indian housing authorities; Independent school districts; Native American tribal governments (Federally recognized); Small businesses; Public and State controlled institutions of higher education; Private institutions of higher education; Special district governments; County governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal organizations (other than Federally recognized tribal governments); Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); State governments; City or township governments; For profit organizations other than small businesses

Contact

National Institutes of Health

PioneerAwards@mail.nih.gov

301-402-2541

Additional details

Funding instrument
Grant
Cost sharing required
No
Archived
Nov 8, 2026

Opportunity number: RFA-RM-27-001

Search this number on Grants.gov for the official listing.