Grants.govNational Institutes of Health

Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics (R01 Clinical Trial Optional)

Posted Nov 18, 2024·open

AGENCY

HHS-NIH11

PROGRAM

Discretionary

AMOUNT

—

CLOSES

Jan 7, 2027

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Description

The goal of the proposed funding announcement is twofold, to promote preclinical and patient based studies examining the mechanism(s) through which incretin mimetics (including agonists or antagonists of GLP-1, GIP-1, or dual GLP-1/GIP-1 agents) impact cancer risk, and to draw talented scientists who understand the dynamic changes caused by these agents to investigate the mechanisms of how these agents influence cancer risk rather than shorter term outcomes such as weight loss and diabetes. The data thus far suggests that these agents may increase the risk of some, while decreasing the risk of other obesity related cancers.

Eligibility

Native American tribal organizations (other than Federally recognized tribal governments); Special district governments; County governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; State governments; Public and State controlled institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Private institutions of higher education; Independent school districts; Small businesses; City or township governments; Native American tribal governments (Federally recognized); Public housing authorities/Indian housing authorities

Contact

National Institutes of Health

grantsinfo@nih.gov

301-402-2541

Additional details

Funding instrument: Grant
Cost sharing required: No
Archived: Feb 12, 2027

Opportunity number: PAR-25-069

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