NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R33 CT Required)
AGENCY
HHS-NIH11
PROGRAM
Discretionary
AMOUNT
Up to $1.5M
CLOSES
Feb 3, 2027
Description
The objective of this funding opportunity is to support investigator-initiated, phase I clinical trials for diagnostic and therapeutic interventions for heart, lung, blood, and sleep (HLBS) disorders in adults and children. The proposed trial can be single or multisite.Applicants applying for funding under this NOFO should be ready to initiate the clinical trial within the first quarter of the project period. Discussion, submission, and attainment of applicable regulatory (FDA, DSMB, IRB) approvals, and establishment of drug (and placebo, if applicable) supplies, and any necessary third-party agreements should be established by the time of award. If time and support for these and other pre-clinical and/or trial readiness activities are desired, applicants should consider the companion NOFO which utilizes an R61/R33 phased approach.
Eligibility
Native American tribal governments (Federally recognized); Public housing authorities/Indian housing authorities; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses; Special district governments; State governments; County governments; Independent school districts; Native American tribal organizations (other than Federally recognized tribal governments); Public and State controlled institutions of higher education; City or township governments; Small businesses; Others (see text field entitled "Additional Information on Eligibility" for clarification)
Contact
Additional details
- Funding instrument
- Grant
- Cost sharing required
- No
- Archived
- Mar 5, 2027
Opportunity number: PAR-25-025
Search this number on Grants.gov for the official listing.