Grants.govNational Institutes of Health

GREGoRi Technology Integration Center (U01, Clinical Trials Optional)

Posted Jun 18, 2026·open

AGENCY

HHS-NIH11

PROGRAM

Discretionary

AMOUNT

Up to $2.3M

CLOSES

Oct 30, 2026

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Description

The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. The purpose of this Notice of Funding Opportunity is to establish the GREGoRi Technology Integration Center, which will enable the development of standards and best practices for applying new and emerging molecular methods in rare disease diagnosis. A major deliverable of the Center will be a multidimensional dataset that can be used for the development and benchmarking of novel tools and strategies that facilitate rare disease diagnosis.

Eligibility

Public and State controlled institutions of higher education; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; State governments; County governments; Native American tribal governments (Federally recognized); Independent school districts; Small businesses; Native American tribal organizations (other than Federally recognized tribal governments); For profit organizations other than small businesses; Public housing authorities/Indian housing authorities; Special district governments; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); City or township governments

Contact

National Institutes of Health

nhgri-gregor@mail.nih.gov

301-402-2541

Additional details

Funding instrument: Cooperative Agreement
Cost sharing required: No
Archived: Dec 29, 2026

Opportunity number: RFA-HG-27-012

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