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Grants.govNational Institutes of Health

Immune Tolerance Network (UM1 Clinical Trial Required)

Posted Oct 20, 2026·open

AGENCY

HHS-NIH11

PROGRAM

Discretionary

AMOUNT

—

CLOSES

Jan 29, 2027

Description

The purpose of this notice of funding opportunity (NOFO) is to support applications to continue the Immune Tolerance Network (ITN). The primary objective of the Network is to develop tolerogenic therapies for immune-mediated disorders. The three main clinical areas of work are: 1) Allergic diseases and asthma; 2) Autoimmune diseases; and 3) Immune-mediated consequences of transplantation. The core functions of the ITN include designing, conducting, and sharing the results of clinical trials and performing integrated mechanistic studies.

Eligibility

Special district governments; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Private institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Small businesses; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; County governments; Independent school districts; City or township governments; Public and State controlled institutions of higher education; Native American tribal governments (Federally recognized); For profit organizations other than small businesses; Native American tribal organizations (other than Federally recognized tribal governments); Public housing authorities/Indian housing authorities; State governments

Contact

National Institutes of Health

ITN_UM1@mail.nih.gov

301-402-2541

Additional details

Funding instrument
Cooperative Agreement
Cost sharing required
No
Archived
Mar 29, 2027

Opportunity number: RFA-AI-28-005

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