The University of California, San Francisco (UCSF or UC San Francisco) is a public land-grant research university in San Francisco, California, United States. It is part of the University of California system and is dedicated entirely to health science and life science. It conducts research and teaching in medical and biological sciences. UCSF was founded as Toland Medical College in 1864. In 1873, it became affiliated with the University of California as its medical department. In the same year, it incorporated the California College of Pharmacy and in 1881 it established a dentistry school.