P30-Core Grant for Vision Research Core B

Functional Genomics & Proteomics (FG&P) Core ABSTRACT The Functional Genomics and Proteomics (FG&P) Core supports research that increases our understanding of how biological function (e.g., vision) arises from the information encoded in an organism's genome. The Core provides support for the design, execution, and analysis of molecular, biochemical, proteomic, and phenotypic experiments in six sections: DNA/RNA services, protein/small molecule analysis, cell culture, ocular/vision structural and functional analysis, rodent ocular microsurgery, and mouse colony services. This support comes largely via the expertise and services of Core personnel, the availability of equipment, supplies, and other Core-dedicated resources, and their training of individuals from laboratories of the Atlanta Vision Research Community (AVRC; Emory University, Georgia Tech, Morehouse School of Medicine, Atlanta VA Healthcare System, and Georgia State University). The FG&P Core provides this support for AVRC investigators who are NEI R01-funded but who cannot justify such services or equipment independently in a single R01-funded project or who are not experts in FG&P techniques. By removing “barriers of entry” that are caused by lack of experience with or lack of access to specialized approaches and equipment, the FG&P Core helps these investigators increase the impact of their research. This support also enhances collaborations across the AVRC by providing uniformity in methodologies supported by the above sections and equal access across institutions. The goal of Drs. Boatright and Pardue is to provide Core use at all times and at all locations to every AVRC investigator. Under their leadership, no AVRC investigator lacks Core support.