← Back to Awards
NIHNATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Identification of Novel Syk/Raf-1 Mediated CLR Ligands as Vaccine Adjuvants
Active
- Institution
- University of Montana, MT
- Principal investigator
- Jay Evans
- Funding
- $1.6M
- Duration
- 2024–2029
39/100
Abstract
The contractor proposes to screen libraries of synthetic putative CLR agonists that induce Th17 or Th17/Th1 immunity as adjuvants for bacterial and fungal pathogens. Age-specific immune phenotyping will be conducted in mice and with human cells and optimized, formulated lead candidates will be tested in models of Mtb and coccidioidomycosis.
LOADING MOONBASE SCORE
Questions for University of Montana
Answered by the team behind this research.
No questions yet. Sign in to ask the first one
Related grants
Same researchers, same institution, scored first.
- NIH · University of Montana55
DEVELOPMENT OF UM-1098: A NOVEL SYNTHETIC TH17 INDUCING ADJUVANT AND DELIVERY SYSTEM
Jay Evans · $1.6M · 2023–2026
- NIH · University of Montana48
Identification of Novel Syk/Raf-1 Mediated CLR Ligands as Vaccine Adjuvants
Jay Evans · $1.6M · 2025–2026
- NIH · University of Montana42
DEVELOPMENT OF UM-1098: A NOVEL SYNTHETIC TH17 INDUCING ADJUVANT AND DELIVERY SYSTEM
Jay Evans · $5.5M · 2023–2028